P2Y12 receptor Mutagenesis Database

Search for mutation:
  • by receptor: hP2Y12

Refine your mapped analysis by selecting one of the following

Functional Mutants

First, please select either a specific value for the Analysis values or select the corresponding checkbox to select all of them. Second, please decide for a standard deviation (SD) for the calculation (default standard deviation is 2).
Analysis Calculation:      BasalEmaxEC50
      SD      SD      SD

Non-functional Mutants

Position(s) where Non-Functional Mutants occur
Position(s) where no Mutations are tolerated

PostHeaderIcon Annotation

Interpretation of Mutation Analysis

Analysis ValueInterpretation
-1significant decrease compared to wildtype
0similar compared to wildtype
1significant increase compared to wildtype