Search for mutation:
  • by receptor: hP2Y12
  • at position: 237

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62376.36LysArgdetails0.1240.0020.9920.0092.2560.0941.291.33
TMH62376.36LysAsndetails0.1140.0060.9720.00910.8330.5390.9811.219
TMH62376.36LysCysdetails0.1250.0010.9610.0182.1120.1481.2971.337
TMH62376.36LysGlndetails0.0910.0120.5760.03636.385.6070.7820.972
TMH62376.36LysSerdetails0.0750.0040.3360.03273.7338.7160.6450.802

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62376.36LysAladetails
TMH62376.36LysAspdetails
TMH62376.36LysGludetails
TMH62376.36LysGlydetails
TMH62376.36LysHisdetails
TMH62376.36LysIledetails
TMH62376.36LysLeudetails
TMH62376.36LysMetdetails
TMH62376.36LysPhedetails
TMH62376.36LysProdetails
TMH62376.36LysThrdetails
TMH62376.36LysTrpdetails
TMH62376.36LysTyrdetails
TMH62376.36LysValdetails