Search for mutation:
  • by receptor: hP2Y12
  • at position: 238

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62386.37ValCysdetails0.1080.0050.7970.03511.2071.0841.0481.156
TMH62386.37ValIledetails0.0960.0030.6310.0026.6810.5590.971.028
TMH62386.37ValLeudetails0.0850.0020.2370.02553.6478.5560.9690.909
TMH62386.37ValMetdetails0.0760.0050.3370.03420.563.5280.9290.809
TMH62386.37ValThrdetails0.0890.0030.2620.0312.4331.1521.0160.957

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62386.37ValAladetails
TMH62386.37ValArgdetails
TMH62386.37ValAsndetails
TMH62386.37ValAspdetails
TMH62386.37ValGlndetails
TMH62386.37ValGludetails
TMH62386.37ValGlydetails
TMH62386.37ValHisdetails
TMH62386.37ValLysdetails
TMH62386.37ValPhedetails
TMH62386.37ValProdetails
TMH62386.37ValSerdetails
TMH62386.37ValTrpdetails
TMH62386.37ValTyrdetails