Search for mutation:
  • by receptor: hP2Y12
  • at position: 239

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62396.38PheGlydetails0.2170.0130.4280.0174.0770.8270.9812.319
TMH62396.38PheLeudetails0.0990.0030.4140.0139.2860.5020.4461.055
TMH62396.38PheMetdetails0.1310.0120.7230.0149.0370.1070.5921.4
TMH62396.38PheTyrdetails0.0910.0020.7080.00639.9431.1350.4140.979

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62396.38PheAladetails
TMH62396.38PheArgdetails
TMH62396.38PheAsndetails
TMH62396.38PheAspdetails
TMH62396.38PheCysdetails
TMH62396.38PheGlndetails
TMH62396.38PheGludetails
TMH62396.38PheHisdetails
TMH62396.38PheIledetails
TMH62396.38PheLysdetails
TMH62396.38PheProdetails
TMH62396.38PheSerdetails
TMH62396.38PheThrdetails
TMH62396.38PheTrpdetails
TMH62396.38PheValdetails