Search for mutation:
  • by receptor: hP2Y12
  • at position: 240

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62406.39IleCysdetails0.1270.0030.610.0047.3280.1821.0441.359
TMH62406.39IleLeudetails0.10.0020.790.00210.2980.3240.8221.07
TMH62406.39IleMetdetails0.1130.0010.6090.0086.0020.3220.9281.207
TMH62406.39IleSerdetails0.0850.0030.2490.00816.5671.8260.6960.905
TMH62406.39IleThrdetails0.1150.0020.5940.0079.4350.3090.9461.231
TMH62406.39IleTrpdetails0.0790.0030.4280.08317.7621.3350.7910.85
TMH62406.39IleValdetails0.1160.0050.870.0153.8620.0740.871.247

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62406.39IleAladetails
TMH62406.39IleArgdetails
TMH62406.39IleAsndetails
TMH62406.39IleAspdetails
TMH62406.39IleGlndetails
TMH62406.39IleGludetails
TMH62406.39IleGlydetails
TMH62406.39IleHisdetails
TMH62406.39IleLysdetails
TMH62406.39IlePhedetails
TMH62406.39IleProdetails
TMH62406.39IleTyrdetails