Search for mutation:
  • by receptor: hP2Y12
  • at position: 241

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62416.40IleLeudetails0.0920.0030.4390.02644.6830.5480.7360.99
TMH62416.40IleValdetails0.0830.0040.2720.01535.133.1980.6210.891

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62416.40IleAladetails
TMH62416.40IleArgdetails
TMH62416.40IleAsndetails
TMH62416.40IleAspdetails
TMH62416.40IleCysdetails
TMH62416.40IleGlndetails
TMH62416.40IleGludetails
TMH62416.40IleGlydetails
TMH62416.40IleHisdetails
TMH62416.40IleLysdetails
TMH62416.40IleMetdetails
TMH62416.40IlePhedetails
TMH62416.40IleProdetails
TMH62416.40IleSerdetails
TMH62416.40IleThrdetails
TMH62416.40IleTrpdetails
TMH62416.40IleTyrdetails