Search for mutation:
  • by receptor: hP2Y12
  • at position: 242

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62426.41IleCysdetails0.1280.0110.9940.02410.7642.1811.3141.371
TMH62426.41IleGlndetails0.0870.0010.4290.00614.3870.1750.6180.931
TMH62426.41IleGlydetails0.0960.0010.2530.003114.4334.4430.6851.032
TMH62426.41IleLeudetails0.0730.0010.4710.0168.3971.2530.6630.781
TMH62426.41IleLysdetails0.0630.0040.1410.04285.64727.9470.5710.673
TMH62426.41IleMetdetails0.1230.0070.9780.0099.3810.2731.261.315
TMH62426.41IlePhedetails0.0820.0010.2760.00394.8139.2970.5820.877
TMH62426.41IleProdetails0.1170.0260.1950.04615.2094.0771.2761.249
TMH62426.41IleSerdetails0.1010.0040.6860.00848.8672.2830.7181.082
TMH62426.41IleThrdetails0.0920.0060.770.00416.8971.8790.8380.988
TMH62426.41IleTrpdetails0.1350.0010.9470.00512.320.1080.9561.44
TMH62426.41IleTyrdetails0.0670.0020.2760.09447.3676.8070.6090.718
TMH62426.41IleValdetails0.0920.0040.7850.02110.4230.9990.920.989

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62426.41IleAladetails
TMH62426.41IleArgdetails
TMH62426.41IleAsndetails
TMH62426.41IleAspdetails
TMH62426.41IleGludetails
TMH62426.41IleHisdetails