Search for mutation:
  • by receptor: hP2Y12
  • at position: 243

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62436.42AlaCysdetails0.1070.0040.8650.0047.1890.3021.0991.146
TMH62436.42AlaGlndetails0.1030.0010.9180.0115.9230.7190.8581.099
TMH62436.42AlaGlydetails0.1410.0070.9910.0073.370.1091.4461.508
TMH62436.42AlaIledetails0.1030.0020.8390.00617.090.9720.851.106
TMH62436.42AlaLeudetails0.1070.0070.8790.0365.8510.3891.0681.147
TMH62436.42AlaMetdetails0.0980.0030.6510.00815.4130.2470.8081.052
TMH62436.42AlaPhedetails0.1050.0070.8740.016.6511.3780.9541.124
TMH62436.42AlaSerdetails0.12700.830.0085.5050.3751.0471.362
TMH62436.42AlaThrdetails0.1080.0010.8470.0096.0560.2491.0771.158
TMH62436.42AlaTrpdetails0.0840.0010.5840.00541.5270.7350.6940.903
TMH62436.42AlaValdetails0.0970.0050.7880.00212.570.8430.9971.04

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62436.42AlaArgdetails
TMH62436.42AlaAsndetails
TMH62436.42AlaAspdetails
TMH62436.42AlaGludetails
TMH62436.42AlaHisdetails
TMH62436.42AlaLysdetails
TMH62436.42AlaProdetails
TMH62436.42AlaTyrdetails