Search for mutation:
  • by receptor: hP2Y12
  • at position: 244

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62446.43ValAspdetails0.1170.0360.2510.05957.147.1561.2771.25
TMH62446.43ValGlndetails0.1140.020.3160.12248.69315.581.2491.222
TMH62446.43ValGludetails0.1520.0020.9810.0027.1950.1591.2521.629
TMH62446.43ValIledetails0.0780.0020.6240.01635.160.4140.7770.835
TMH62446.43ValLysdetails0.090.010.3920.06636.5133.2810.820.966
TMH62446.43ValSerdetails0.0950.0070.2220.01523.3472.8891.0351.013
TMH62446.43ValThrdetails0.1220.0060.7940.0157.7810.6371.1071.305

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62446.43ValAladetails
TMH62446.43ValArgdetails
TMH62446.43ValAsndetails
TMH62446.43ValCysdetails
TMH62446.43ValGlydetails
TMH62446.43ValHisdetails
TMH62446.43ValLeudetails
TMH62446.43ValMetdetails
TMH62446.43ValPhedetails
TMH62446.43ValProdetails
TMH62446.43ValTrpdetails
TMH62446.43ValTyrdetails