Search for mutation:
  • by receptor: hP2Y12
  • at position: 245

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62456.44PheSerdetails0.0820.0060.1630.01810.0750.6730.8990.88
TMH62456.44PheTyrdetails0.0830.0020.360.02521.7672.8620.6580.885

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62456.44PheAladetails
TMH62456.44PheArgdetails
TMH62456.44PheAsndetails
TMH62456.44PheAspdetails
TMH62456.44PheCysdetails
TMH62456.44PheGlndetails
TMH62456.44PheGludetails
TMH62456.44PheGlydetails
TMH62456.44PheHisdetails
TMH62456.44PheIledetails
TMH62456.44PheLeudetails
TMH62456.44PheLysdetails
TMH62456.44PheMetdetails
TMH62456.44PheProdetails
TMH62456.44PheThrdetails
TMH62456.44PheTrpdetails
TMH62456.44PheValdetails