Search for mutation:
  • by receptor: hP2Y12
  • at position: 246

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62466.45PheAladetails0.1460.0180.8370.0452.8660.2671.4561.564
TMH62466.45PheAsndetails0.10.0130.3810.0999.153.2461.0931.07
TMH62466.45PheCysdetails0.2010.0070.980.0051.4050.1181.6822.153
TMH62466.45PheGlydetails0.1560.0050.9510.0061.9710.1380.7041.665
TMH62466.45PheIledetails0.1180.0040.8840.0032.580.0611.1721.259
TMH62466.45PheLeudetails0.1030.0020.8590.0037.9870.4280.4681.107
TMH62466.45PheMetdetails0.1070.0010.9190.0073.150.1420.4861.149
TMH62466.45PheProdetails0.2080.0080.9660.0032.1790.2771.7362.223
TMH62466.45PheSerdetails0.3050.0150.9890.0080.8920.1752.283.271
TMH62466.45PheThrdetails0.3190.0071.0280.010.7940.0531.4433.412
TMH62466.45PheValdetails0.160.0050.980.0191.350.0320.7241.711

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62466.45PheArgdetails
TMH62466.45PheAspdetails
TMH62466.45PheGlndetails
TMH62466.45PheGludetails
TMH62466.45PheHisdetails
TMH62466.45PheLysdetails
TMH62466.45PheTrpdetails
TMH62466.45PheTyrdetails