Search for mutation:
  • by receptor: hP2Y12
  • at position: 247

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62476.46IleCysdetails0.1060.0010.5290.0035.1670.1760.4781.13
TMH62476.46IleLeudetails0.1190.0020.780.03121.271.1521.2151.271
TMH62476.46IleMetdetails0.0880.0020.2860.00213.3131.4440.3990.943
TMH62476.46IlePhedetails0.1760.0060.7550.0048.3841.4950.7961.881
TMH62476.46IleProdetails0.0930.0010.4930.00617.8270.7020.420.993
TMH62476.46IleThrdetails0.1390.0060.950.01210.3590.3331.4171.483
TMH62476.46IleValdetails0.1180.0210.8950.0437.1910.4310.8811.264

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62476.46IleAladetails
TMH62476.46IleArgdetails
TMH62476.46IleAsndetails
TMH62476.46IleAspdetails
TMH62476.46IleGlndetails
TMH62476.46IleGludetails
TMH62476.46IleGlydetails
TMH62476.46IleHisdetails
TMH62476.46IleLysdetails
TMH62476.46IleSerdetails
TMH62476.46IleTrpdetails
TMH62476.46IleTyrdetails