Search for mutation:
  • by receptor: hP2Y12
  • at position: 248

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH62486.47CysAsndetails0.1310.0040.4850.02113.740.4891.0441.405
TMH62486.47CysMetdetails0.0730.0010.2960.00856.0671.1810.6070.777
TMH62486.47CysSerdetails0.1150.0030.640.01218.860.4270.9191.236

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH62486.47CysAladetails
TMH62486.47CysArgdetails
TMH62486.47CysAspdetails
TMH62486.47CysGlndetails
TMH62486.47CysGludetails
TMH62486.47CysGlydetails
TMH62486.47CysHisdetails
TMH62486.47CysIledetails
TMH62486.47CysLeudetails
TMH62486.47CysLysdetails
TMH62486.47CysPhedetails
TMH62486.47CysProdetails
TMH62486.47CysThrdetails
TMH62486.47CysTrpdetails
TMH62486.47CysTyrdetails
TMH62486.47CysValdetails