Search for mutation:
  • by receptor: hP2Y12
  • at position: 292

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH72927.47CysAladetails0.0910.0110.7740.0610.0811.6440.8160.977
TMH72927.47CysGlydetails0.0740.0020.310.06930.55717.1671.0190.793
TMH72927.47CysIledetails0.0720.0030.8230140.8130.9960.775
TMH72927.47CysThrdetails0.0640.0030.220.0221.1798.2580.7420.686
TMH72927.47CysValdetails0.0880.0050.8660.0314.8080.3051.2160.946

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH72927.47CysArgdetails
TMH72927.47CysAsndetails
TMH72927.47CysAspdetails
TMH72927.47CysGlndetails
TMH72927.47CysGludetails
TMH72927.47CysHisdetails
TMH72927.47CysLeudetails
TMH72927.47CysLysdetails
TMH72927.47CysMetdetails
TMH72927.47CysPhedetails
TMH72927.47CysProdetails
TMH72927.47CysSerdetails
TMH72927.47CysTrpdetails
TMH72927.47CysTyrdetails