Search for mutation:
  • by receptor: hP2Y12
  • at position: 293

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH72937.48LeuAladetails0.0730.0040.3980.01822.1174.39310.778
TMH72937.48LeuIledetails0.1180.010.750.0278.9090.8430.991.263
TMH72937.48LeuMetdetails0.0950.010.4390.07519.5873.3230.8011.022
TMH72937.48LeuValdetails0.0860.0120.5460.05316.4573.8890.9930.918

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH72937.48LeuArgdetails
TMH72937.48LeuAsndetails
TMH72937.48LeuAspdetails
TMH72937.48LeuCysdetails
TMH72937.48LeuGlndetails
TMH72937.48LeuGludetails
TMH72937.48LeuGlydetails
TMH72937.48LeuHisdetails
TMH72937.48LeuLysdetails
TMH72937.48LeuPhedetails
TMH72937.48LeuProdetails
TMH72937.48LeuSerdetails
TMH72937.48LeuThrdetails
TMH72937.48LeuTrpdetails
TMH72937.48LeuTyrdetails