Search for mutation:
  • by receptor: hP2Y12
  • at position: 294

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH72947.49AspAsndetails0.0990.0080.3450.06744.66640.3310.8311.061
TMH72947.49AspGlndetails0.1170.0020.880.0134.271.0091.0431.25
TMH72947.49AspGludetails0.110.0120.8530.0298.4710.7060.9251.18
TMH72947.49AspSerdetails0.1070.0030.4480.03425.2711.890.8981.145

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH72947.49AspAladetails
TMH72947.49AspArgdetails
TMH72947.49AspCysdetails
TMH72947.49AspGlydetails
TMH72947.49AspHisdetails
TMH72947.49AspIledetails
TMH72947.49AspLeudetails
TMH72947.49AspLysdetails
TMH72947.49AspMetdetails
TMH72947.49AspPhedetails
TMH72947.49AspProdetails
TMH72947.49AspThrdetails
TMH72947.49AspTrpdetails
TMH72947.49AspTyrdetails
TMH72947.49AspValdetails