Search for mutation:
  • by receptor: hP2Y12
  • at position: 296

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH72967.51PheAladetails0.1750.020.9160.0292.5240.2141.7831.875
TMH72967.51PheCysdetails0.3550.0131.0250.0250.4670.0443.6123.798
TMH72967.51PheIledetails0.280.0290.9750.0150.3350.0293.2473.003
TMH72967.51PheLeudetails0.1540.0030.9160.0071.5250.4531.5641.644
TMH72967.51PheMetdetails0.1980.0150.9810.0090.7120.0222.0182.121
TMH72967.51PheThrdetails0.0830.0080.6120.03313.7831.3520.9580.886
TMH72967.51PheTrpdetails0.0780.0060.5290.03612.3431.0250.7990.84
TMH72967.51PheValdetails0.3360.0130.9950.0130.5130.0263.423.596

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH72967.51PheArgdetails
TMH72967.51PheAsndetails
TMH72967.51PheAspdetails
TMH72967.51PheGlndetails
TMH72967.51PheGludetails
TMH72967.51PheGlydetails
TMH72967.51PheHisdetails
TMH72967.51PheLysdetails
TMH72967.51PheProdetails
TMH72967.51PheSerdetails
TMH72967.51PheTyrdetails