Search for mutation:
  • by receptor: hP2Y12
  • at position: 298

Highlight result values


Functional parameterin red belowin green above
E_min (MV)
E_min (SEM)
E_max (MV)
E_max (SEM)
EC_50 (MV) [nM]
EC_50 (SEM) [nM]
MV E_min_mt / MV E_min_wt (per experiment day)
MV E_min_mt / MV E_min_wt (total)

Results


Functional Mutants

SubstructureNoBa-WewildtypemutantE_min (MV)E_min (SEM)E_max (MV)E_max (SEM)EC_50 (MV) [nM]EC_50 (SEM) [nM]MV E_min_mt / MV E_min_wt (per experiment day)MV E_min_mt / MV E_min_wt (total)
TMH72987.53TyrAladetails0.0970.0020.8830.0214.2040.6651.1031.043
TMH72987.53TyrCysdetails0.1230.0120.8760.0629.4222.0981.1041.322
TMH72987.53TyrProdetails0.0730.0050.2380.04169.137.7640.8320.783
TMH72987.53TyrSerdetails0.1080.0040.9020.013.6490.141.2291.156

Non-functional Mutants

SubstructureNoBa-Wewildtypemutant
TMH72987.53TyrArgdetails
TMH72987.53TyrAsndetails
TMH72987.53TyrAspdetails
TMH72987.53TyrGlndetails
TMH72987.53TyrGludetails
TMH72987.53TyrGlydetails
TMH72987.53TyrHisdetails
TMH72987.53TyrIledetails
TMH72987.53TyrLeudetails
TMH72987.53TyrLysdetails
TMH72987.53TyrMetdetails
TMH72987.53TyrPhedetails
TMH72987.53TyrThrdetails
TMH72987.53TyrTrpdetails
TMH72987.53TyrValdetails